FlavScents AInsights Entry for Hotrienol (CAS: 20053-88-7)

1. Identity & Chemical Information

• Common Name(s): Hotrienol
• IUPAC Name: 3,7-dimethyl-1,5-octadien-3-ol
• CAS Number: 20053-88-7
• FEMA Number: Not available
• Other Identifiers: FL number not available; CoE number not available; IFRA reference not available
• Molecular Formula: C10H18O
• Molecular Weight: 154.25 g/mol
• Functional Groups and Structure–Odor Relevance: Hotrienol is a monoterpene alcohol, which contributes to its floral and green odor profile. The presence of the hydroxyl group is significant for its solubility and interaction with other fragrance components.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

• Odor and Flavor Descriptors: Hotrienol is characterized by a floral, green, and slightly citrus-like aroma. It is often described as having a fresh, sweet, and slightly herbal scent.
• Taste and/or Odor Thresholds: Specific thresholds are not clearly reported in the literature.
• Typical Sensory Role: Hotrienol serves as an impact note in fragrance compositions, providing a fresh and floral top note that enhances the overall bouquet.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

• Known Natural Sources: Hotrienol is naturally found in various essential oils, including those of lavender and thyme.
• Formation Pathways: It is typically formed through the enzymatic degradation of terpenes in plants.
• Relevance to “Natural Flavor” or “Natural Fragrance” Designation: Due to its natural occurrence in essential oils, hotrienol can be labeled as a natural flavor or fragrance component.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

• Flavor Categories and Applications: Hotrienol is used in flavor formulations for its floral and green notes, often in applications such as beverages, candies, and baked goods.
• Functional Role in Flavor Systems: It acts as a modifier, enhancing the freshness and floral aspects of the flavor profile.
• Typical Use Levels: Documented use levels are not available; however, industry-typical use levels are estimated to be in the range of 0.1–10 ppm in finished products.
• Stability Considerations: Hotrienol is relatively stable under normal conditions but may degrade under high heat or acidic conditions.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

• Fragrance Families and Product Types: Hotrienol is commonly used in floral and green fragrance families, suitable for perfumes, soaps, and personal care products.
• Functional Role: It serves as a top note, providing freshness and floral character.
• Typical Concentration Ranges: Typically used at concentrations of 0.1–1% in fragrance formulations.
• Volatility and Top/Middle/Base Contribution: Hotrienol is a volatile compound contributing primarily to the top note of a fragrance.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States (FDA / FEMA GRAS): Not explicitly listed as GRAS by FEMA.
• European Union (Reg. (EC) No 1334/2008; FL number status): Not specifically listed under EU regulations.
• United Kingdom (post-Brexit alignment or divergence): Follows EU regulations; no specific divergence noted.
• Asia (Japan, China, ASEAN): Regulatory status not clearly reported; typically follows international guidelines.
• Latin America (e.g., Brazil, MERCOSUR): No specific information available; generally aligns with international standards.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: No specific ADI or MSDI values are available; considered safe at typical flavor use levels.
• Dermal Exposure: No significant irritation or sensitization reported; IFRA guidelines should be consulted for specific use levels.
• Inhalation Exposure: Generally considered safe for use in fragrances; no occupational exposure limits specifically reported.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

• Why This Material is Valuable: Hotrienol is valued for its ability to impart a fresh, floral character to both flavors and fragrances.
• Typical Synergies: Works well with other floral and citrus notes, enhancing the overall freshness and complexity.
• Common Formulation Pitfalls: Overuse can lead to an overpowering floral note; balance with other components is crucial.
• Situations Where It is Frequently Over- or Under-Used: Often under-used in complex formulations where its subtlety can be lost.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

• Well-Established Data: The sensory profile and natural occurrence are well-documented.
• Industry-Typical but Undocumented Practices: Use levels and regulatory status often rely on industry norms rather than explicit documentation.
• Known Data Gaps or Regulatory Ambiguities: Specific regulatory approvals and toxicological data are limited.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• “Citation hooks:” line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-09-22 13:12:02 GMT (p2)