FlavScents AInsights Entry for 2-methyl-1,5-hexadiene (CAS: 27477-37-8)

1. Identity & Chemical Information

• Common Name(s): 2-methyl-1,5-hexadiene
• IUPAC Name: 2-methylhex-1,5-diene
• CAS Number: 27477-37-8
• FEMA Number: Not available
• Other Identifiers: Not available
• Molecular Formula: C7H12
• Molecular Weight: 96.17 g/mol

2-methyl-1,5-hexadiene is a hydrocarbon compound characterized by its two double bonds and a methyl group attached to the second carbon. The presence of these functional groups contributes to its reactivity and potential odor characteristics, although specific odor relevance is not well-documented.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

2-methyl-1,5-hexadiene is not widely recognized for its sensory properties in flavor or fragrance applications. As a hydrocarbon, it may possess a mild, generic odor typical of alkenes, but specific descriptors, intensity, or diffusion characteristics are not well-documented in the literature. Its role in sensory applications, if any, is likely minimal or as a background component.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

2-methyl-1,5-hexadiene is not commonly found in nature and is typically synthesized for industrial purposes. It does not have a significant role in natural flavor or fragrance designations. Its formation is generally through synthetic organic chemistry methods rather than natural biosynthetic pathways.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

There is limited information on the use of 2-methyl-1,5-hexadiene in flavor applications. It is not a common flavoring agent and does not have established use levels in food or beverages. Its stability under various conditions such as heat, pH, and oxidation is not well-documented, suggesting limited utility in flavor systems.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

2-methyl-1,5-hexadiene is not typically used in fragrance formulations. It lacks distinctive odor characteristics that would make it a valuable component in fragrance families or product types. Its volatility and contribution to fragrance profiles are not well-documented, indicating it is not a significant ingredient in perfumery.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States: Not listed as FEMA GRAS
• European Union: Not specifically regulated under Reg. (EC) No 1334/2008
• United Kingdom: No specific post-Brexit regulatory alignment or divergence noted
• Asia: Limited information available; not commonly used
• Latin America: No specific regulatory information available

2-methyl-1,5-hexadiene does not have explicit approvals for use in flavors or fragrances and is not commonly addressed in regional regulatory frameworks.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: Data not found; not typically used in food applications
• Dermal Exposure: Data not found; not typically used in fragrance applications
• Inhalation Exposure: Data not found; not typically used in applications with significant inhalation exposure

Given its limited use in consumer products, detailed toxicological data is scarce. Formulators should verify safety through standard industry practices and consult relevant safety data sheets.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

2-methyl-1,5-hexadiene is not a common material in flavor or fragrance formulation. Its value lies primarily in industrial applications rather than consumer products. Formulators should be aware of its limited sensory impact and regulatory status when considering its use.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on 2-methyl-1,5-hexadiene is limited, with most information derived from industrial chemical databases rather than flavor or fragrance-specific sources. There are significant gaps in sensory, regulatory, and toxicological data, reflecting its minimal use in consumer products.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges: Not applicable due to lack of data
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: Not applicable as this is a single compound

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-02-17 15:03:40 GMT (p2)