AInsights Entry for (Z)-12-musk decenone (CAS: 111879-79-9)
1. Identity & Chemical Information
- Common Name(s): (Z)-12-musk decenone
- IUPAC Name: (Z)-1-(3,3-dimethylcyclohexyl)dec-1-en-3-one
- CAS Number: 111879-79-9
- FEMA Number: Not available
- Other Identifiers: Not available
- Molecular Formula: C16H28O
- Molecular Weight: 236.39 g/mol
- Functional Groups and Structure-Odor Relevance: (Z)-12-musk decenone is characterized by its cyclohexyl and ketone functional groups, contributing to its musky odor profile. The presence of the (Z)-configuration in the double bond is crucial for its olfactory properties, providing a distinctive musk scent that is less sharp compared to its (E)-isomer.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
- Odor and Flavor Descriptors: (Z)-12-musk decenone is known for its musky, animalic odor with a subtle floral undertone. It is often described as having a warm, rich, and slightly sweet scent.
- Taste and/or Odor Thresholds: Specific thresholds are not clearly reported, but it is generally used in trace amounts due to its potent odor.
- Typical Sensory Role: It serves as an impact note in perfumery, providing depth and warmth to fragrance compositions.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
- Known Natural Sources: (Z)-12-musk decenone is not typically found in nature and is primarily synthesized for use in fragrances.
- Formation Pathways: It is synthesized through chemical processes involving cyclohexyl ketones and alkenes.
- Relevance to “Natural Flavor” or “Natural Fragrance” Designation: As a synthetic compound, it does not qualify for natural flavor or fragrance designations.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
- Flavor Categories and Applications: While primarily used in fragrances, it can be used in flavor applications to impart a musky note, although this is less common.
- Functional Role in Flavor Systems: It acts as a background realism enhancer in certain flavor profiles.
- Typical Use Levels: Data not found. Industry-typical use is in trace amounts due to its potent aroma.
- Stability Considerations: It is relatively stable under normal conditions but may degrade under extreme heat or acidic conditions.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
- Fragrance Families and Product Types: Commonly used in oriental, woody, and floral fragrance families.
- Functional Role: Acts as a base note, providing longevity and depth to the fragrance.
- Typical Concentration Ranges: Typically used at concentrations of 0.1% to 1% in fragrance formulations.
- Volatility and Top/Middle/Base Contribution: It is a base note with low volatility, contributing to the lasting power of the fragrance.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
6. Regulatory Status (Regional Overview)
- United States (FDA / FEMA GRAS): Not explicitly listed as GRAS for flavor use.
- European Union (Reg. (EC) No 1334/2008; FL number status): Not listed under the EU flavoring regulations.
- United Kingdom: Follows EU regulations post-Brexit with no specific divergence reported.
- Asia (Japan, China, ASEAN): Regulatory status not clearly reported; typically follows international guidelines.
- Latin America (e.g., Brazil, MERCOSUR): Not specifically regulated; follows general fragrance regulations.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
- Oral Exposure: Not typically used in food applications; therefore, oral exposure data is limited.
- Dermal Exposure: Generally considered safe for dermal use in fragrances at typical concentrations. No significant irritation or sensitization reported.
- Inhalation Exposure: Low volatility reduces inhalation risk; however, standard safety precautions should be followed in occupational settings.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
- Why This Material is Valuable: Provides a unique musky note that enhances the depth and complexity of fragrance compositions.
- Typical Synergies: Blends well with floral and woody notes, enhancing their richness.
- Common Formulation Pitfalls: Overuse can lead to an overpowering scent; balance is key.
- Situations Where It is Frequently Over- or Under-used: Often under-used in lighter fragrances where its depth could add complexity.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
- Well-Established Data: The musky odor profile and its use in fragrances are well-documented.
- Industry-Typical but Undocumented Practices: Use levels and specific applications may vary based on proprietary formulations.
- Known Data Gaps or Regulatory Ambiguities: Limited data on flavor use and specific regulatory approvals.
Citation hooks: FlavScents
QA Check
- All required sections 1-9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- If complex natural material: includes section 5a (not applicable here)
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-06-01 17:13:25 GMT (p2)