FlavScents AInsights Entry: para-Anisyl Acetate (CAS: 104-21-2)

1. Identity & Chemical Information

• Common Name(s): para-Anisyl acetate
• IUPAC Name: 4-Methoxyphenyl acetate
• CAS Number: 104-21-2
• FEMA Number: 2086
• Other Identifiers: FL No. 09.013
• Molecular Formula: C9H10O3
• Molecular Weight: 166.17 g/mol

Para-anisyl acetate is an ester compound characterized by the presence of a methoxy group attached to a phenyl ring, which is further linked to an acetate group. This structural configuration contributes to its sweet, floral aroma, often associated with hawthorn and mimosa. The methoxy group enhances its olfactory properties, making it a valuable component in both flavor and fragrance formulations.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

Para-anisyl acetate is known for its sweet, floral, and slightly balsamic odor profile. It is often described as reminiscent of hawthorn and mimosa, with a moderate intensity and good diffusion properties. The compound serves as an impact note in formulations, providing a distinct floral character that can enhance the overall sensory experience. While specific taste and odor thresholds are not widely documented, its potency suggests it is effective at low concentrations.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

Para-anisyl acetate is naturally found in several plant species, including hawthorn and mimosa. It can also be formed through the esterification of anisyl alcohol with acetic acid. This compound is relevant to "natural flavor" and "natural fragrance" designations when derived from natural sources, aligning with consumer preferences for naturally sourced ingredients.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

Para-anisyl acetate is utilized in various flavor categories, particularly in floral and sweet profiles. It is commonly used in confectionery, beverages, and baked goods to impart a floral note. Typical use levels in finished products range from 1 to 10 ppm, with higher concentrations potentially overpowering other flavor components. The compound is stable under typical processing conditions, though it may degrade under extreme heat or acidic environments.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

In the fragrance industry, para-anisyl acetate is employed across multiple fragrance families, including floral, oriental, and gourmand. It acts as a modifier and impact note, contributing to the top and middle notes of a fragrance composition. Typical concentration ranges in perfumes and personal care products vary from 0.1% to 1%, depending on the desired intensity and product type. Its moderate volatility allows it to blend well with other fragrance components.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States: Recognized as GRAS by FEMA for flavor use.
• European Union: Listed under Regulation (EC) No 1334/2008 with an assigned FL number.
• United Kingdom: Regulatory status aligns with the EU post-Brexit.
• Asia: Approved for use in Japan and China, with specific concentration limits.
• Latin America: Generally accepted in Brazil and MERCOSUR countries, subject to local regulations.

Explicit approvals and harmonized assumptions are common, though formulators should verify country-specific guidelines to ensure compliance.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

Para-anisyl acetate is considered safe for use in both flavor and fragrance applications when used within recommended limits. Oral exposure through flavor use is supported by FEMA GRAS status, with an acceptable daily intake (ADI) not specifically established but considered low risk. Dermal exposure in fragrance products is generally well-tolerated, with no significant irritation or sensitization reported. Inhalation exposure is minimal due to its moderate volatility, though occupational safety measures should be observed in manufacturing settings.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

Para-anisyl acetate is valued for its ability to impart a distinct floral character to both flavors and fragrances. It synergizes well with other floral and sweet notes, enhancing the overall complexity of a formulation. Common pitfalls include overuse, which can lead to an overpowering scent or flavor. It is often under-utilized in formulations seeking a subtle floral nuance.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on para-anisyl acetate is well-established, with comprehensive sensory and regulatory information available. Industry practices are well-documented, though specific numeric thresholds for sensory perception may require further research. Regulatory ambiguities are minimal, with clear guidelines provided by major authorities.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-09-21 15:21:43 GMT (p2)